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Active liver disease, which may include unexplained persistent transaminase elevations, is a contraindication to the use of rosuvastatin see contraindications 4 .
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However, this intermediate, to be converted to rosuvastatin, must be hydrolized and thus during this step rosuvstatin may racemize, thereby decreasing the optical purity of the final compound.
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The doses chosen for the study were generally recommended start doses of rosuvastatin 10 mg and atorvastatin 20 mg .
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each round, biconvex, pink coloured, film-coated tablet embossed with r112 on one side and rph on the other side, contains rosuvastatin calcium equivalent to 20 mg rosuvastatin.